The regrettable truth is that we live in a time of increasingly severe disruption of the ecosystems of our planet. As those disruptions worsen, more pathogenic microbial organisms will flow upward out of those disrupted ecological matrices into the human species. (Almost always this jump originates from a region-specific animal species.) The current emerging pathogen that is raising concern is known as SARS-Cov-2 – the infection which it causes is called Covid-19. And yes, it is confusing that it is Cov-2 when the virus is discussed but Covid-19 when it becomes an infection. (Just because a bunch of people get advanced degrees does not mean they are sensible or know how to talk to people who actually live in the real world.)
Not that the following description will be of any real use to those of us on the (non-Ph.D.) front lines, corona viruses are enveloped, positive-stranded RNA viruses which have the largest genome of all all viruses. (See, that doesn’t help at all.) Like most RNA viruses they regularly engage in recombination of their genetic code – that is they continually make new variants of themselves. Viruses are one of the most highly adaptable organisms on this planet.
Despite the existence of a few antiviral pharmaceuticals the only real treatment that western medicine has developed
for viral infections is the creation of vaccines. Unfortunately vaccines for new organisms generally take a year or so to develop (which is why a Covid-19 vaccine is going to take awhile and will probably be, like the original SARS vaccine, only partially effective). And because viral organisms (such as influenza) tend to continually rearrange their genome, new vaccines for things like the flu have to be made every year. Viral pathogens are almost always far harder to deal with using western medical paradigms than bacteria (which are themselves proving harder to rationally control than originally believed).
There are perhaps a dozen or two known corona viruses, only seven or so (at this time) are known to infect people. The first one that raised serious international concern was SARS (Sudden Acute Respiratory Syndrome). The new, pandemic coronavirus is a very close relative which is why it’s called SARS-Cov- 2. As with the original SARS organism, it is a serious pathogen when it begins to spread among large numbers of people. Unfortunately, SARS-Cov-2 is a far more aggressive pathogen than the original SARS virus. An analysis of the first 75,000 people who were infected found that it has a mortality rate of around 2.3%, making it some 23 times more fatal than seasonal flu infections (which is why a worldwide pandemic could be very serious indeed). Like influenza organisms this virus primarily affects the lungs and is spread most often through respiratory droplets – though direct contact with body secretions can also transmit it.
As with the majority of respiratory viruses, infection stimulates coughing and sneezing which enables the virus to find more hosts. (Many people who are infected have minor or no symptoms, so that they act as stealth carriers, spreading the virus throughout the population.)
Unfortunately, the virus can also survive for a relatively long time on most surfaces, thus being transmitted in some cases by touch.
SARS and MERS (Middle East Respiratory Syndrome – caused by a related viral pathogen) also tend to infect the GI tract in people who become ill. Around a quarter of those infected develop a rather intense diarrhea. Early studies of the new virus have found viral particles in stool samples which indicates it might also spread via feces (as SARS and MERS do) and most likely in urine (again like SARS and MERS).
As with SARS, Cov-2 has a sort-of distinct three-stage impact on lung tissue once someone is infected: initial infection that allows viral replication, immune response which can include in more serious cases immune hyper-reactivity, and relatively minor to very severe pulmonary damage. That being said, most infections tend to be very much like the flu. Most people will in fact believe themselves to have the flu – not a coronavirus infection. In reality, Cov-19 infections for around three quarters of those infected will remain relatively mild. Only about 18% of those infected experience a severe infection. Most of those will be older, that is people whose immune systems have aged over time; people with compromised immune systems; and people with existing disease conditions such as COPD.
Somewhat oversimplified, here is what serious Cov-19 infections do in the lungs. Once in the lungs the virus infects specific cells, among them the cilia. The cilia can be likened to tiny hairs. They protrude from cells in the lungs and continually move like waves on the ocean. This moves mucus and particulate matter up and out of the lungs.
During infection, SARS viruses often kill the cilia they infect which allows debris and fluids to build up in the lungs (this is pneumonia). When the infection becomes this serious the immune system can become highly activated. This sends large numbers of immune cells to the lungs to stop the infection, clear out the debris, and heal the tissues.
Oversimplified (again), during infection the affected cells send out chemical messenger molecules which (despite their being a variety of them with different names) I group together under the single name of cytokines. (Really, at root, this is just a tomato tomahto kind of thing; they are all messenger molecules that do stuff in the body during infections.)
When the Cov-2 virus finds its preferred cells it uses very specific and evolutionarily ancient strategies to get inside those cells, take them over, and use their structures to reproduce. Then it breaks the cells open, releasing new viruses into the body which can go on to infect other cells, and so on, ad nauseum. Along the way it stimulates coughing to infect more mammals to spread the virus into new hosts.
It is important to realize that viruses are some of the oldest living things on the planet (despite this many biologists continue to insist viruses are not “alive,” which as anyone with a brain can plainly see is inaccurate).
Viruses are billions of years old. As such, they are exceptionally good at what they do, and, like all living things, they learn as they go, adapting new behaviors along the way.
Plants, in comparison, are only about a billion years old, complex land plants around 300 million years or so. In contrast our most ancient hominid ancestors are at most 1-2 million years old, our species in the form it has now is only around 35,000 years old. Western medicine (at a generous estimate) is 200 hundred years old. Its knowledge of viral pathogens and infections is only around 50 years old. Much of that is rudimentary or even incorrect (based as it is on outdated ecological models and medical understandings).
All pathogens are sophisticated at modulating human cytokines to achieve their own ends. They have learned how to circumvent many of our normal immune responses in order to facilitate their entry into the body, their reproduction, and their release into new hosts. Elderly and compromised immune systems are quite often unable to respond sufficiently to these viral sophistications; they get overwhelmed.
Natural Protocols for SARS-group Viral Infections, Including COV-19
The rationale here is to find plants that will counteract the actions of the SARS-group of viruses, then to cross correlate those in order to choose the plants that are present in most categories of action and that have a tradition of use for these kinds of infections. What is needed are plants that have the following actions:
1) Plants specifically antiviral for the SARS-group of viruses; the strongest known so far are Scutellaria baicalensis (Chinese skullcap root), Houttuynia spp, Isatis spp, Glycyrrhiza spp (licorice), Forsythia suspensa (the fruit), Sophora flavescens, and Lycoris radiata (extremely potent). Lonicera japonica and Polygonum cuspidatum are also effective as antivirals for coronaviruses as a group.
2) Block viral attachment to ACE-2 linkages. Specific for this are Glycyrrhiza spp (licorice), Scutellaria baicalensis (Chinese skullcap root), Sambucus spp (elder), luteolin, Aesculus hippocastanum (horse chestnut), Polygonum cuspidatum (Japanese knotweed root), Rheum officinale, and plants high in procyanidins and lectins (e.g. Cinnamomum, i.e. cinnamon).
3) Upregulate and protect ACE-2 expression, increase its activity (esp in the aged), and lower Ang-2. Herbs specific for this are Pueria spp (kudzu), Salvia miltiorrhiza (Dan shen), and Ginkgo biloba. Use ACE inhibitors (in contrast to ACE-2 upregulators) to increase the presence of ACE-2 and help protect the lungs from injury: Crataegus spp (hawthorn) and Pueraria spp (kudzu) are specific.
4) Modulate cytokine responses (Salvia miltorrhiza), including the lowering of TGF levels [Angelica sinensis (dong quai), Astragalus monghilicus], regulating HMGB1 (Salvia miltiorrhiza), and reducing IL-1b [Polygonum cuspidatum (Japanese knotweed), Scutellaria baicalensis (Chinese skullcap), Cordyceps spp, Pueraria (kudzu), and Eupatorium perfoliatum (boneset)].
5) Protect lung cells from hypoxia (Rhodiola spp).
6) Protect the cilia (Cordyceps spp, olive oil and leaf, any berberinecontaining plants, and Bidens pilosa).
7) Reduce autoimmunity and increase healthy immune function (Rhodiola, Astragalus spp, Cordyceps spp).
8) Protect endothelial cells (Polygonum cuspidatum – Japanese knotweed root).
9) Protect spleen and lymph system [Ceanothus spp (red root), Phytolacca (poke root), Scutellaria baicalensis (Chinese skullcap root), Salvia miltiorrhiza, Bidens pilosa].
10) Stimulate DC maturation (Cordyceps spp) and increase T cell counts [Glycyrrhiza spp (licorice), Ceanothus (red root), Sambucus spp (elder), and zinc].
General protective: Shuanghuanglian formulation. (Note: this was found in the earlier SARS outbreak in China to help considerably – a review of the already mentioned mechanisms indicates why. It is now being tested in clinical trials in China for treatment of Cov-19 infections). The formulation is composed of Forsythia suspensa fruit (2 parts), Lonicera japonica (1 part), Scutellaria baicalensis (1 part). Suggested dosage: 1 tsp 3x daily. (I would also take with this the immune formulation from the following protocol in order to activate the most effective healthy immune function for this particular viral pathogen.) SARS-group Treatment Protocol: This is composed of three tincture formulations, as follows.
1) Core formulation: Scutellaria baicalensis (3 parts), Polygonum cuspidatum (2 parts), Pueraria (2 parts), Glycyrrhiza (1 part), decocted Sambucus leaf tincture (1 part). Dosage: 1 tsp 3x day, if acute 1 tsp 6x day.
2) Immune formulation: Cordyceps (3 parts), Angelica senensis (2 parts), Rhodiola (1 part), Astragalus (1 part). Dosage: Same as number one.
3) Cellular protection/cytokine modulation/spleen-lymph support: Salvia miltiorrhiza (3 parts), Ceanothus (2 parts), Bidens pilosa (1 part). Dosage: Same as number one.
Some Comments on Preparation of the Formulas
“Part” refers to how much of the plant matter is used. So, if you already have the tinctures, then – if you are working with fluid ounces (i.e., 30 ml for metric people) for the core formulation you would blend together three ounces of Scutellaria baicalensis, two ounces each of the tinctures of Polygonum cuspidatum and Pueraria, and one ounce each of the tinctures of Glycyrrhiza and decocted Sambucus leaf. The dosage would be as above for the tincture combination. (Please note if you want to make your own tinctures, please see the medicine making chapter of my book Herbal Antibiotics, second edition, or any equivalent source.)
Copyright © 2020, Stephen Harrod Buhner, All Rights Reserved.